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Comparison of two medicaments MTA and recombinant platelet derived growth factor(rh PDGF BB) in Deep caries management

Efficacy of MTA and Recombinant human platelet derived growth factor(rh PDGF- BB) as pulp treatment agents - A randomized controlled trial. - Nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/081352
Enrollment
24
Registered
2025-02-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Pulp capping treatment : Group1:Recombinant Platelet Derived Growth Factor-BB IOPA will be taken after 1 month , 3 months and after 6 months ,CBCT will be taken,Dentin bridge assessme

Sponsors

Dr ANITHA T
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Class 1 caries in maxillary and mandibular first and second molar with deep caries. Radiographs showing caries approximating pulp will be included. Asymptomatic patients with no tenderness to percussion, positive response to electric pulp testing, and cold test. Normal periodontal status clinically and radiographically will be included.

Exclusion criteria

Exclusion criteria: Patients with any Systemic disease will be excluded. History of spontaneous and nocturnal pain. Teeth showing negative response to electric pulp testing and cold test. Teeth with radiographic evidence of pulpal degeneration, resorption, and periapical changes.

Design outcomes

Primary

MeasureTime frame
clinical success( no subjective symptoms,no top,mobility,no swelling) Radiographic success- absence of pulpal and periapical pathologiesTimepoint: 6th month

Secondary

MeasureTime frame
Presence or absence of dentin bridge formation & volume of formed dentin bridge in cubic mmTimepoint: 6th month

Countries

India

Contacts

Public ContactDr Karthick K

KSR Institute of Dental Science and Research,Tiruchengode

drkarthickendo@ksridsr.edu.in9843659053

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026