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Comparing Pain After Single Visit Root Canal Treatment Using Cold and Room Temperature Irrigating Solutions- A Clinical Study

Comparative Evaluation Of Post Endodontic Pain In Single Visit Root Canal Treatment Using Cryo Treated And Room Temperature Saline and Dexamethasone Solution As Final Irrigants: A Randomized Clinical Trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/081348
Enrollment
104
Registered
2025-02-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K04- Diseases of pulp and periapical tissues

Interventions

Intervention1: single dose of 2ml of 4mg/ml cold Dexamethasone solution as intracanal irrigant.: Post endodontic pain assessment after using single dose of 2ml of 4mg/ml cold dexamethasone solution as

Sponsors

Sejal Jindal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Single rooted single canal teeth. 2 Patients with symptomatic irreversible pulpitis. 3 Patients with pain level 4 or higher on NRS. 4 Teeth with mature root apex 5 Age group 18- 60 years

Exclusion criteria

Exclusion criteria: 1 Primary endodontic failures/ re-treatment. 2 Teeth with evidence of internal or external root resorption, root fracture, calcification, open apices and periapical lesion. 3 Teeth not suitable to undergo single visit root canal treatment. 4 Medically compromised patients and pregnant women. 5 Patients with history of medicine intake including NSAIDs, antibiotics, corticosteroids, opioids, sedatives, anti-anxiety or anti-depressants in past 6 hours. 6 Patients who refuse to participate in the study.

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the post endodontic pain of patients undergoing single visit endodontics after using saline at room temperature, cold saline (cryo treated), dexamethasone at room temperature and cold dexamethasone (cryo treated) as final irrigants in single visit root canal treatment.Timepoint: 6 hours,12 hours,24 hours,48 hours

Secondary

MeasureTime frame
Analgesic intake, evaluated by the number of analgesic tablets taken in post-operative pain. Having an unscheduled appointment for emergency treatment or any complications such as post-operative swelling.Timepoint: 6 hours,12 hours,24 hours,48 hours

Countries

India

Contacts

Public ContactSejal Jindal

Bhojia Dental College and Hospital

drhimanilau@gmail.com7982908801

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026