Health Condition 1: S062- Diffuse traumatic brain injury
Conditions
Interventions
None listed
Sponsors
AIIMS, New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age 18-65 yrs 2.Either sex 3.ASA Physical status I/II/III 4.Patient admitted within 48hrs of TBI 5.Moderate to severe TBI (GCS = 12 after resuscitation) 6.Patients undergoing invasive ICP monitoring with a sustained rise in ICP refractory to medical management.
Exclusion criteria
Exclusion criteria: 1.ASA physical status IV/ V 2.Any brain mass lesion requiring immediate 3.decompression 4.Patients with dilated unreactive pupils 5.Non-traumatic intracranial mass lesion 6.Past H/o any intracranial surgery 7.Coagulation abnormality 8.Unstable cervical spine injury 9.Pregnant and lactating patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare jugular venous oximetry values before and after decompressive craniectomy (DC)Timepoint: multiple readings will be taken at multiple timepoints starting before DC to 24 hours after DC. | — |
Secondary
| Measure | Time frame |
|---|---|
| To correlate the lowest values of SjVO2 with the outcome (GOSE) at discharge and at 3 months To correlate changes in values of SjVO2 with outcome (GOSE) at discharge and at 3 months To correlate values of SjVO2 and ICP (pre- and post-decompressive craniectomy) To correlate changes in AVDO2, AVDG and VADL values with the outcome (Pre-operative, Intra-operative just after the dural opening, and post-operative at 1, 6 & 24 h) Timepoint: Multiple readings will be taken at multiple timepoints starting before DC to 24hrs after DC | — |
Countries
India
Contacts
Public ContactDr Navdeep Sokhal
AIIMS New Delhi
Outcome results
None listed