Ultrasound guided vs conventional fluid resuscitation in sepsis patients with shock presenting to emergency

Comparative analysis of ultrasound guided fluid resuscitation versus conventional fluid resuscitation in predicting fluid responsiveness through serum lactate levels in sepsis patients presenting to emergency room with shock. A randomized control trial study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/081289

Enrollment

202

Registered

2025-02-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B998- Other infectious disease

Interventions

Intervention1: USG guided fluid resuscitation: Study population that is, patients in sepsis with shock will be divided in to two limbs. one limb will receive ultrasound guided fluid resuscitation. Con

Eligibility

Inclusion criteria

Inclusion criteria: All patients of age more than or equal to 16 years presenting to AIIMS Patna emergency room in sepsis with shock

Exclusion criteria

Exclusion criteria: Traumatic shock patient Known case of congestive cardiac failure with poor left ventricular function Known case of decompensated liver and kidney disease Cardiac tamponade Concomitant attack of a severe airway disease like asthma or chronic obstructive pulmonary disease that may have confounded the IVC interpretation Pneumothorax Any intrathoracic malignancy Massive pleural effusion Adrenal insufficiency Patients on medications like metformin, valproate etc which increases serum lactate level Pregnancy Patient with denial consent

Design outcomes

Primary

Measure	Time frame
To compare six-hour lactate clearance between USG guided fluid resuscitation and conventional fluid resuscitation in patients presenting to emergency room in sepsis with shock.Timepoint: 6th hour of presentation to emergency	—

Secondary

Measure	Time frame
Comparison of the following between USG guided fluid resuscitation & conventional fluid resuscitation in patients presenting to emergency room in shock with sepsis. Resuscitation time Maximum noradrenaline dose used within 6 hours Total fluid given within 6hoursTimepoint: 6th hour of presentation to emergency room	—

Countries

India

Contacts

Public ContactGowtham P G

AIIMS Patna

dr.deepak11706@aiimspatna.org8075317558

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026