A study comparing the effectiveness of two different doses of Dexmedetomidine combined with Levobupivacaine in supraclavicular brachial plexus block using peripheral nerve stimulator guidance

A comparative randomized double blind study of two different doses of Dexmedetomidine combined with Levobupivacaine in supraclavicular brachial plexus block under peripheral nerve stimulator guidance - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/081240

Enrollment

100

Registered

2025-02-24

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue Health Condition 2: M00-M99- Diseases of the musculoskeletal system and connective tissue Health Condition 3: M00-M99- Diseases of the musculoskeletal system and connective tissue

Interventions

Intervention1: supraclavicular brachial plexus block: To compare efficacy of two different doses of dexmedetomidine in supraclavicular brachial plexus block Intervention2: supraclavicular brachial ple

Eligibility

Inclusion criteria

Inclusion criteria: Age between 18 to 60 years ASA physical status I and II Patients scheduled for elective open reduction and internal fixation of fracture both bones forearm after obtaining written/informed consent from the patients

Exclusion criteria

Exclusion criteria: Known allergy to local anaesthetic agents(known hypersensitivity to study drugs) Traumatic nerve injury History of respiratory disorders History of neuromuscular diseases History of cardiovascular diseases Bleeding disorders or patients on anticoagulant therapy Hepatic or renal failure Pregnant and lactating women Drug abusers and psychiatry patients

Design outcomes

Primary

Measure	Time frame
To compare the duration of analgesia between the two groupsTimepoint: every 30 minutes up to 24 hours till block is completely worn off	—

Secondary

Measure	Time frame
To compare the onset of sensory and motor blockade between the two groups To compare the duration of sensory and motor blockade between the two groups To compare hemodynamic variables between the two groups To compare the number of rescue analgesics in 24 hours in both groups To compare adverse effects between the two groupsTimepoint: sensory and motor blockade was assessed every 2 minutes after completion of injection till 30 minutes later every 30 minutes after the completion of surgery till the first 12 hours and thereafter hourly until the block had completely worn off Hemodynamics were recorded at 0 minutes 5 minutes 10 minutes 15 minutes 30 minutes 1 hour 2 hours 6 hours 12 hours and 24 hours postoperative pain was assessed using VAS for every hour till the block lasted	—

Measure

Time frame

To compare the onset of sensory and motor blockade between the two groups To compare the duration of sensory and motor blockade between the two groups To compare hemodynamic variables between the two groups To compare the number of rescue analgesics in 24 hours in both groups To compare adverse effects between the two groupsTimepoint: sensory and motor blockade was assessed every 2 minutes after completion of injection till 30 minutes later every 30 minutes after the completion of surgery till the first 12 hours and thereafter hourly until the block had completely worn off Hemodynamics were recorded at 0 minutes 5 minutes 10 minutes 15 minutes 30 minutes 1 hour 2 hours 6 hours 12 hours and 24 hours postoperative pain was assessed using VAS for every hour till the block lasted

—

Countries

India

Contacts

Public ContactDonthu Balaji

Government medical college kadapa

dr.balaji.donthu@gmail.com9505319721

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026