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Study on effects of Short-term Head-Down Tilt and Handgrip on Heart Rate and Blood Pressure changes in Active and Sedentary Young Adults.

An Experimental study for Assessment of effects of Short-term 6 degree Head-Down Tilt with/without superimposed Isometric handgrip on Cardiovascular Variabilities in Physically Active and Sedentary Young Adults - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/081211
Enrollment
102
Registered
2025-02-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 6 degree Head-down Tilt: 5 minutes Intervention2: Isometric Handgrip: 11 minutes Intervention3: 6 degree head-down tilt superimposed with isometric handgrip: 5 minutes Control Intervent

Sponsors

AIIMS Rishikesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Healthy individuals willing to participate in study

Exclusion criteria

Exclusion criteria: Systolic BP more than 140mmHg and Diastolic BP more than 90 mm Hg. Complaints of syncope. Symptoms of Autonomic function disorder(Screening through questionnaire) Structural heart disease or any other CVS disorder (Myocardial infarction, Congestive Heart Failure). Chronic illness (Diabetes Mellitus, Chronic kidney disease, Chronic liver disease) Major surgeries in past 6 months. History of increased intraocular pressure/ocular surgery in past 6 months. Intake of drugs that have effect on autonomic nervous system. Professional athletes (vigorous exercise more than 1 hour in a day)

Design outcomes

Primary

MeasureTime frame
Change in heart rate and blood pressure during 6 degree Head-down tilt.Timepoint: At baseline—

Secondary

MeasureTime frame
Change in Heart Rate Variability (HRV), Blood Pressure Variability (BPV), & Baroreceptor Sensitivity (BRS) during a 6 Head-down Tilt. Effect of isometric handgrip on HRV, BPV, & BRS during 6 HDTTimepoint: At baseline—

Countries

India

Contacts

Public ContactDr Ashutosh Kashyap

AIIMS Rishikesh

poorvi.physio@aiimsrishikesh.edu.in8126182374

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026