Using dexmedetomidine as a mist before surgery to help keep the heart rate and blood pressure steady during intubation.

evaluation of nebulised dexmedetomidine in blunting hemodynamic response to intubation -a prospective randomised study - nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/081137

Enrollment

Registered

2025-02-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z768- Persons encountering health services in other specified circumstances

Interventions

Intervention1: nebulised dexmedetomidine: pre operative dexmedetomidine nebulisation 1mcg/kg 5ml for blunting the hemodynamic responses of laryngoscopy and intubation Intervention2: nebulised dexmedet

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 and 2 elective surgeries under general anaesthesia with endotracheal intubation patient giving valid informed consent

Exclusion criteria

Exclusion criteria: 1.asa 3 & 4 2.pregnancy 3.renal failure

Design outcomes

Primary

Measure	Time frame
to evaluate the changes in MAP values after as a component of hemodynamic stress response to laryngoscopy and intubation with nebulised dexmedetomidine.Timepoint: 15minutes to 30minutes	—

Secondary

Measure	Time frame
Timepoint:	—

Countries

India

Contacts

Public ContactDr Lakshmi A

vinayaka missions medical college and hospitals,salem

sabapathyv.appavoo@gmail.com9442566989

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026