Comparing the Effects of Adding Dexmedetomidine to Bupivacaine versus Using Bupivacaine Alone in Nerve Blocks for Shoulder Surgery

Comparative study to evaluate the effect of dexmeditomedine as adjuvant to 0.5% bupivacaine with 0.5% plain bupivcaine under USG guided interscalene brachial plexus block for patient undergoing shoulder arthroscopy under general anaesthesia. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/081136

Enrollment

Registered

2025-02-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 4- Measurement and Monitoring

Interventions

Intervention1: Dexmeditomedine as adjuvant to 0.5% bupivacaine: Effect of Dexmedetomidine as adjuvant to 0.5% bupivacaine will be assessed for post-operative analgesia in patients of interscalene bra

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with ASA physical status I & II will be considered for inclusion. 2.Patients who are scheduled to undergo elective shoulder arthroscopy will be eligible. 3.Individuals aged between 18 and 65 years old will be included in the study. 4.Patients who express a willingness to actively participate in the study will be considered for enrollment.

Exclusion criteria

Exclusion criteria: 1.Patients who refuse to participate will be excluded from the study. 2.Individuals with known allergies to local anesthetics and opioids will not be included. 3.Patients with a local infection at the site of the intended block will be excluded. 4.Pregnant women will not be eligible for participation. 5.Individuals with severe cardiopulmonary diseases will be excluded from the study. 6.Patients with neurological deficits in the arm selected for surgery will not be considered. 7.Individuals with bleeding disorders or those currently on anticoagulant medications will be excluded from participation.

Design outcomes

Primary

Measure	Time frame
The duration of post-operative analgesia with dexmeditomedine as adjuvant to 0.5% bupivacaine will be significantly more as compared to 0.5% plain bupivcaine.Timepoint: Assessments will be done at 30 min, 1 hour, 2, 3,4,5 and 6 hours. Study will be conducted over a period of 2 years.	—

Secondary

Measure	Time frame
Intraoperative Hemodynamic stability and Side Effects Timepoint: Intraoperative Hemodynamic stability will be assessed at 5mins, 15 mins, 30 mins , 1 hr and 2 hrs. 2. evaluation of the occurrence of any adverse effects.	—

Countries

India

Contacts

Public ContactDr Karuna Taksande

Datta Meghe Institute of Higher Education and Research

karunahp1878@gmail.com7722037738

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026