Comparative evaluation of effect of C-PRF and i-PRF on acceleration of tooth movement

Assessment of the effectiveness of concentrated platelet-rich fibrin (C-PRF) and injectable platelet-rich fibrin (i-PRF) on the rate of orthodontic tooth movement: a comparative in-vivo study. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/081083

Enrollment

Registered

2025-02-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K039- Disease of hard tissues of teeth,unspecified

Interventions

Intervention1: Concentrated-Platelet rich fibrin: C-PRF will be injected intraligamentary just before the retraction phase and the acceleration in rate of tooth movement will be evaluated for 4 months

Eligibility

Inclusion criteria

Inclusion criteria: 1. Class I Bimaxillary cases needing all 4 extractions 2. Between age group of 14 to 30years

Exclusion criteria

Exclusion criteria: 1. Patients under any other medication which affects tooth movement 2. Patients with craniofacial anomalies 3. Patients with periodontal disease 4. Patients with any kind of systemic disease that affects tooth movement 5. Patients in pregnancy or lactation 6. Patients with habits of smoking and alcoholism

Design outcomes

Primary

Measure	Time frame
Acceleration rate of tooth movementTimepoint: At baseline, after 1month, after 2months, after 3months, after 4months	—

Secondary

Measure	Time frame
Root resorption & tooth vitalityTimepoint: Just before intervention & after 4 months	—

Countries

India

Contacts

Public ContactT Uttam Kumar

Faculty of Dental Sciences, Ramaiah University of Applied Sciences

pacchi77@yahoo.com9886242624

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026