Comparison of two novel methods for pain relief for breast surgery

Comparison of pecto-intercostal fascial block and erector spinae plane block for post-operative pain relief in patients undergoing modified radical mastectomy - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/081065

Enrollment

Registered

2025-02-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50- Malignant neoplasm of breast Health Condition 2: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: pecto-intercostal fascial blocK, erector spinae plane block: After induction under general anaesthesia, pateint will bw given either of the pecto-intercostal fascial block or erector sp

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients suffering from carcinoma breast of either gender. 2.American Society of Anaesthesiologists (ASA) physical status I –II. 3.Age ranging from 18-80 years

Exclusion criteria

Exclusion criteria: 1.Patient refusal. 2.History of relevant drug allergy. 3.History of psychiatric illness and substance abuse. 4.Patient suffering from severe cardiovascular, respiratory, liver, metabolic or neurological disease. 5.Pregnant patient. 6.Coagulopathy. 7.Infection at planned injection site 8.Use of chronic pain medications or neuro-modulatory medications. 9.Inability of the patient to understand and interpret visual analogue scale

Design outcomes

Primary

Measure	Time frame
To evaluate the reduction in pain intensity in post-operative period by using linear visual analogue scale (VAS) score in patients receiving either PIF block or ESP block following MRM.Timepoint: 30 minutes, 1 hour, 4 hour, 8 hour, 12 hour and 24 hour	—

Secondary

Measure	Time frame
1. To calculate and compare cumulative morphine consumption over 24 hours in post-operative period in both the groups 2. To calculate and compare the total dose of antiemetics over 24 hours in both the groups 3. To monitor and compare any changes in hemodynamic variables in peri-operative period 4. To compare the safety profile of both the blocks and note any side effects pertaining to the procedure or the drugs used in the present study Timepoint: 30 minutes, 1 hour, 4 hours, 8 hours, 12 hours, 24 hours	—

Measure

Time frame

1. To calculate and compare cumulative morphine consumption over 24 hours in post-operative period in both the groups 2. To calculate and compare the total dose of antiemetics over 24 hours in both the groups 3. To monitor and compare any changes in hemodynamic variables in peri-operative period 4. To compare the safety profile of both the blocks and note any side effects pertaining to the procedure or the drugs used in the present study Timepoint: 30 minutes, 1 hour, 4 hours, 8 hours, 12 hours, 24 hours

—

Countries

India

Contacts

Public ContactDr Richa Saroa

Government Medical College and Hospital, Sector 32, Chandigarh

sanjeev_palta@yahoo.com9646121523

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026