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Effect of Dexmedetomidine on Reducing Arrhythmias After Long Cardiopulmonary Bypass

Role of Dexmedetomidine in reduction of arrhythmias post long cardiopulmonary bypass exposure

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/081063
Enrollment
176
Registered
2025-02-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I499- Cardiac arrhythmia, unspecified

Interventions

Intervention1: Dexmedetomidine: Dexmedetomidine administered at a dose of 1 g/kg over 10 minutes during rewarming in cardiopulmonary bypass surgery. Control Intervention1: Not applicable: Not applica

Sponsors

Dr Kamna Nagar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective valve replacement surgery 2. Adult patients scheduled for congenital cardiac surgery 3. Patients providing written informed consent

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Reduction in the incidence of arrhythmias post long cardiopulmonary bypass exposure. This includes monitoring ECG changes, heart rate, and the occurrence of arrhythmias (such as premature ventricular contractions, atrial fibrillation, and ventricular tachycardia) before induction, during surgery, and in the postoperative ICU period.Timepoint: 36 weeks

Secondary

MeasureTime frame
1. Advantage in fast-tracking recovery , Evaluating whether dexmedetomidine facilitates earlier extubation & ICU discharge. 2. Reduction in the use of long acting anti-arrhythmic drug infusions Specifically assessing the decreased need for amiodarone or other anti-arrhythmic medications postoperatively.Timepoint: 1 year

Countries

India

Contacts

Public ContactDR Dinesh Kaushal

King Georges Medical University Lucknow

dineshkaushal91@yahoo.com9839089242

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026