Health Condition 1: G431- Migraine with aura Health Condition 2: G430- Migraine without aura
Conditions
Interventions
Control Intervention1: Amitriptyline prophylaxis: assessing its effect on HRV and lipid profile
Amitriptyline: 10mg- 100mg per day, orally
Frequency: OD or BD, it will be decided on case to case basis
Sponsors
Dr. Robin Reji
Eligibility
Inclusion criteria
Inclusion criteria: Newly diagnosed case of Migraine, according to the International Classification of Headache Disorders (ICHD-3) criteria Those who have given written informed consent for the study
Exclusion criteria
Exclusion criteria: History of significant cardiovascular disease (e.g., myocardial infarction, arrhythmias, heart failure) Patients with diabetes, HTN, dyslipidemia, Kidney and liver disease who are currently on medication Patients currently taking statins or other lipid-lowering therapies Patients with a history of severe psychiatric disorders Pregnant or breastfeeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. changes in HRV on Amitriptyline and Propranolol prophylaxis Timepoint: changes to be observed after 3 months of follow up after recruitment | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. change in lipid profile on Amitriptyline and Propranolol prophylaxis 2. Clinical response to migraine severity on propranolol and amitriptyline prophylaxisTimepoint: changes to be observed after 3 months of follow up after recruitment | — |
Countries
India
Contacts
Public ContactROBIN REJI
Outcome results
None listed