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Success Rate of Two Different Antibiotic Treatments for Saving Decayed Baby Teeth: A Triple-Blinded, Randomized Study

Survival Rate of Lesion Sterilization and Tissue Repair Using Triple Antibiotic and Double Antibiotic Paste in Primary Molars: A Triple-Blinded, Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/081024
Enrollment
158
Registered
2025-02-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: -

Interventions

Intervention1: Group-1: Patients will be treated with 3-mix paste and will act as the working control.: Children aged 4 8 years with compromised, infected primary molars indicated for LSTR will be sel

Sponsors

PMS College of Dental Science and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Advanced root resorption more than two-thirds. Severe bone loss in the furcal and periapical area due to pulpitis. Pathologic mobility due to periapical infection from pulpities. Radiolucency in the furcal area. Patients not willing for extraction. Presence of abscess Presence of sinus

Exclusion criteria

Exclusion criteria: Children with systemic disease. Children with allergies to antibiotics. Developmentally and medically compromised children. Teeth with perforated floor. Excessive bone loss in the furcation area extending to the crypt of underlying tooth bud. Non-restorable crown

Design outcomes

Primary

MeasureTime frame
Clinical Criteria: Immediate post-operative absence of spontaneous pain No tenderness to percussion No mobility No intraoral or extraoral swelling No sinus tract Radiographic Criteria: Internal root resorption External root resorption Bone resorption / Peri-radicular radiolucency Cyst formationTimepoint: Resolution of clinical signs and symptoms will be evaluated using the index within one month after treatment. At each subsequent visit, clinical and radiographic evaluations will be conducted every 6 months for a period of 2 years.

Secondary

MeasureTime frame
Survival Rate Evaluation: Categorization of success and failure will be defined and calculated using the validated composite index. Timepoint: first month,every 6 months for a period of 2 years

Countries

India

Contacts

Public ContactDr Shaniya Sain

Department of Pediatric and Preventive Dentistry,PMS College of Dental Science and Research

drsajeenajosek@gmail.com9447823844

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026