Health Condition 1: F322- Major depressive disorder, singleepisode, severe without psychotic features
Conditions
Interventions
None listed
Sponsors
JSAyurveda Mahavidhyalaya
Eligibility
Inclusion criteria
Inclusion criteria: Participants newly diagnosed with depression based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria. The diagnosis must be confirmed by a licensed psychiatrist, and the participants must have been diagnosed within the last seven days. Cognitive Ability: Participants must demonstrate sufficient cognitive ability to understand and respond to study questions. This will be assessed using the Clock Drawing Test, a brief cognitive screening tool, before inclusion. Willingness to Participate: Participants must provide informed consent and agree to complete all study procedures and assessments. Healthy Controls (for Control Group): Adults between the ages of eighteen and thirty-five years with no history of psychiatric disorders. Participants must meet the criteria for good health status as determined by the Swasthya Assessment Scale of CCRAS. Inclusivity: Participants will be included irrespective of their gender, socioeconomic status, or educational background.
Exclusion criteria
Exclusion criteria: Severe Psychiatric Disorders: Individuals with severe psychiatric disorders such as schizophrenia or bipolar disorder. Substance Abuse: Individuals with a history of substance abuse or dependence. Neurological Disorders: Individuals with diagnosed neurological conditions (e.g., Parkinson s disease, multiple sclerosis, epilepsy) that could directly affect cognitive function. Chronic Illnesses: Individuals with chronic medical conditions (e.g., hypertension, diabetes, heart disease) that may indirectly influence cognitive function over time. Pregnancy and Lactation: Female participants who are currently pregnant or in the lactating period. Interfering Medications: Individuals currently taking medications known to interfere with depression treatment (e.g., certain antidepressants, and antipsychotics). Non-compliance: Individuals who do not have the ability or willingness to comply with study requirements, including attending appointments and following treatment protocols. Cognitive Impairment: Individuals demonstrating significant cognitive impairment as determined by the Clock Drawing Test, indicating they may be unable to reliably participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is to evaluate the correlation between the status of Jatharagni and depression.Timepoint: 54 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the Jatharagni status between newly diagnosed depression patients and healthy controls. To assess the overall health status of healthy controls using the Swasthya Assessment Scale of CCRAS.Timepoint: 54 weeks | — |
Countries
India
Contacts
Public ContactBarad Vatsal Harajbhai
J.S.Ayurveda Mahavidhyalaya
Outcome results
None listed