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Comparative study of PRF and bone graft and gum surgery with bone drilling for the regrowth of bone in bone loss patients

Comparative evaluation of open flap debridement with intramarrow penetration with and without PRF and Bone graft in the treatment of horizontal bone defect- A clinico radiographical study - Nil

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080957
Enrollment
18
Registered
2025-02-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: PRF membrane: open flap debridement and intramarrow penetration will be done and then PRF membrane will be placed over the defect area Intervention2: xenograft: open flap debridement an

Sponsors

Dr Suchitra B
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects who are diagnosed with stage II chronic periodontitis with horizontal defects.Patients with periodontal pocket depths ranging from 5 to 6 mm

Exclusion criteria

Exclusion criteria: Systemically compromised patients. Use of antibiotics in the past 6 months Steroid or inflammatory drugs for 7 days in 3 months Known allergy to the above mentioned drugs/substance Smokers and alcoholic Pregnant and lactating women Periodontal therapy within 6 months

Design outcomes

Primary

MeasureTime frame
To evaluate the efficacy of clinical and radiographical parameters in open flap debridement and intramarrow penetration alone and with platelet rich fibrin and bone graft.Timepoint: all clinical parameters and radiographic analysis should be done at baseline, 3 months and 6 months

Secondary

MeasureTime frame
To compare the results of clinical and radiographical parameters in open flap debridement and intramarrow penetration alone and with platelet rich fibrin and bone graft.Timepoint: all clinical parameters and radiographic analysis should be done at baseline, 3 months and 6 months and compare their results

Countries

India

Contacts

Public ContactDr Amit K walvekar

coorg institute of dental sciences

suchibarath@gmail.com7812034749

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026