Effect of breathing and oral exercises in patients with breathing issues during sleep

Effect of comprehensive rehabilitation on apnea hypopnea index in patients with severe obstructive sleep apnea: a pre-post study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080946

Enrollment

Registered

2025-02-20

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J398- Other specified diseases of upperrespiratory tract

Interventions

Intervention1: Comprehensive Rehabilitation: Functional Nasal Breathing Rehabilitation techniques Myofunctional Therapy Diaphragmatic Breathing Exercise Frequency - 3 times/day for 5 days a week Durat

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with severe OSA 2. BMI less than 40 kg/m2

Exclusion criteria

Exclusion criteria: 1. Patients with obstructive nasal disease such as allergic rhinitis. 2. Individuals with craniofacial malformations. 3. Patients diagnosed with comorbid sleep disorders such as insomnia, restless leg syndrome. 4. Pregnant women 5. Patients with history of pharyngeal surgery. 6. Patients with history of congestive heart failure, cardiomyopathy, chronic obstructive pulmonary disease, liver cirrhosis. 7. Patients with history of neuromuscular disorders such as myasthenia gravis, motor neuron disease, demyelinating diseases. 8. Patients with history of stroke. 9. Patients with psychiatric illness such as schizophrenia, anxiety disorder, obsessive compulsive disorder, bipolar disorder, attention deficit disorder and hyperactivity disorder. 10. Consumption of alcoholic beverages regularly. 11. Periodontal disease (gingivitis) 12. Temporomandibular Joint dysfunction

Design outcomes

Primary

Measure	Time frame
1. Apnea Hypopnea Index 2. Epworth Sleepiness ScaleTimepoint: 1. At baseline (0 weeks), End of the treatment (12 weeks) 2. At baseline (0 weeks), End of the treatment (12 weeks), Follow up (24 weeks	—

Secondary

Measure	Time frame
Oxygen Desaturation IndexTimepoint: At baseline (0 weeks), End of the treatment (12 weeks);Snoring IndexTimepoint: At baseline (0 weeks), End of the treatment (12 weeks);Pittsburg Sleep Quality IndexTimepoint: At baseline (0 weeks), End of the treatment (12 weeks), Follow up (24 weeks);Manual Assessment of Respiratory MotionTimepoint: At baseline (0 weeks), End of the treatment (12 weeks), Follow up (24 weeks);Breath Hold TestTimepoint: At baseline (0 weeks), End of the treatment (12 weeks), Follow up (24 weeks);Self Evaluation of Breathing QuestionnaireTimepoint: At baseline (0 weeks), End of the treatment (12 weeks), Follow up (24 weeks)	—

Measure

Time frame

Oxygen Desaturation IndexTimepoint: At baseline (0 weeks), End of the treatment (12 weeks);Snoring IndexTimepoint: At baseline (0 weeks), End of the treatment (12 weeks);Pittsburg Sleep Quality IndexTimepoint: At baseline (0 weeks), End of the treatment (12 weeks), Follow up (24 weeks);Manual Assessment of Respiratory MotionTimepoint: At baseline (0 weeks), End of the treatment (12 weeks), Follow up (24 weeks);Breath Hold TestTimepoint: At baseline (0 weeks), End of the treatment (12 weeks), Follow up (24 weeks);Self Evaluation of Breathing QuestionnaireTimepoint: At baseline (0 weeks), End of the treatment (12 weeks), Follow up (24 weeks)

—

Countries

India

Contacts

Public ContactDr Prem V

Manipal College of Health Professions, Manipal Academy of Higher Education

prem.v@manipal.edu9886647732

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026