Comparing the effectiveness of regional nerve block under ultrasound guidance where one group of patients is given Ketamine with bupivacaine and second group is given dexamethasone with bupivacaine is patient undergoing total laproscopic hysterectomy for post operative pain relief.

Effectiveness of Ultrasound guided- Transverse Abdominis Plane Block using Ketamine with Bupivacaine versus Dexamethasone with Bupivacaine for post operative analgesia in patient undergoing Total Laproscopic Hysterectomy- a prospective randomized double blinded study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080918

Enrollment

Registered

2025-02-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system

Interventions

Intervention1: Ketamine: Injection Ketamine (0.5 mg/kg) diluted with normal saline as an additive with 5 ml of injection 0.5% bupivacaine (total volume 10 on each side)given in transverse abdominis p

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age 30-70yrs Patients under ASA I and ASA II Patient undergoing elective total laproscopic hysterectomy

Exclusion criteria

Exclusion criteria: Patient s refusal to participate in the study Patient taking anticoagulants Have an allergy or contraindication to the drug used Alcohol or drug abuse Have infection near the block site Have clinically significant neurological, cardiovascular, renal or hepatic disease. ASA III-IV patients Having mental disorder which interferes with visual analogue scale (VAS) evaluation were excluded from the study

Design outcomes

Primary

Measure	Time frame
To measure the duration of post operative analgesia and time required for primary dose of rescue analgesic after surgery. To compare nad assess pain scores with bupivacaine plus ketamine versus bupivacaine plus dexamethasone post surgery surgery.Timepoint: Pain scores at 0, 2, 6, 8, 12, 24 hours post surgery.	—

Secondary

Measure	Time frame
Vital monitoring( heart rate, BP & spO2) during intra operative period. Patient satisfaction score(excellent, good, fair, poor) Side effects or any complications.Timepoint: Vital monitoring (HR, BP, spo2)at 0,5,10,15,30,60,90,120 minutes intra operatively post intubation. Patient satisfaction score at 0, 2, 4,6, 12,24 hours post extubation.	—

Countries

India

Contacts

Public ContactSara Zubair

Institute of medical science and sum hospital

dr.diptimayee2010@gmail.com9861159151

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026