A clinical trial to study the effect of Homoeopathic preparation of Gymnema sylvestre mother tincture, 6C and 30C in patients of Diabetes mellitus type 2

Phytochemical screening of Gymnema sylvestre mother tincture and validation of the hypoglycemic effect of Gymnema sylvestre mother tincture, 6C and 30C in patients of Diabetes mellitus type 2 with HbA1c parameter: An open label randomized controlled clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080905

Enrollment

Registered

2025-02-19

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Gymnema sylvestre mother tincture, Gymnema sylvestre 6C and Gymnema sylvestre 30 C: Gymnema sylvestre mother tincture 10 drop in half cup of distilled water three times in a day orally

Eligibility

Inclusion criteria

Inclusion criteria: Patients of different religions and socioeconomic groups. Patients who are untreated before and have opted for homoeopathic treatment. Patient who have already had other medication but now intend to undergo homoeopathic treatment. Confirmed cases of diabetes mellitus type 2 patients. Patients with Glycosylated haemoglobin (HbA1c) is equal to or greater than 6.5 %, Post prandial blood sugar (PPBS) is equal to or greater than 11.1 mmol/l (200 mg/dl) and Fasting blood sugar (FBS) is equal to or greater than 7.0 mmol/l (126 mg/dl) in type 2 diabetes mellitus. Patient willing to undergo laboratory investigations whenever required. Patient willing to give written consent for participating in the study and complete follow-up during study.

Exclusion criteria

Exclusion criteria: Patient taking medicines for diabetes mellitus type 2 complications. Patients suffering from any life threatening illness or any major complication of diabetes mellitus type 2 and other associated co-morbities. Patients not willing to undergo any investigations, even after advised. Pregnancy. Patients whose blood glucose level were not controlled within 3 months after giving Homoeopathic medicine Gymnema sylvestre mother tincture or Gymnema sylvestre 6C or Gymnema sylvestre 30C.

Design outcomes

Primary

Measure	Time frame
Glycosylated hemoglobin (HbA1c)Timepoint: at baseline, 3 months and 6 months.	—

Secondary

Measure	Time frame
Post prandial blood sugar (PPBS) & Fasting blood sugar (FBS).Timepoint: at baseline, 3 months & 6 months.	—

Countries

India

Contacts

Public ContactDr Gitasri Pal

National Institute of Homoeopathy

Drrajanih@gmail.com9163955737

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026