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A clinical trial to study the impact of intraoperative timing and administration of paracetamol on postoperative shivering.

Impact of intraoperative timing and administration of paracetamol on postoperative shivering : A randomised double blind controlled trial. - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080851
Enrollment
255
Registered
2025-02-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj.Paracetamol: Inj.Paracetamol 15mg/kg will be administered 15 minutes after induction of anaesthesia. Intervention2: Inj. Paracetamol: Inj.Paracetamol 15mg/kg will be administered 30

Sponsors

Sri Ramachandra Institute of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I/II adult patients of either gender undergoing elective surgical procedures performed under General Anaesthesia. Expected duration of surgery between 1 and 4 h

Exclusion criteria

Exclusion criteria: Surgeries more than 4 hour duration. Those having body mass index more than 35 kg/m2. Evidence of liver dysfunction. History of allergy to Paracetamol. Body temperature more than 38 C or less than 36 C.

Design outcomes

Primary

MeasureTime frame
The incidence of shivering.Timepoint: The incidence of shivering will be assessed every 30 minutes postoperatively up to a period of 4 hours.

Secondary

MeasureTime frame
The incidence of perioperative hypothermia (temperature less than 36 C)Timepoint: Core temperature will be monitored every 15 minutes after induction of anaesthesia till the completion of surgery & every 30 minutes after completion of surgery up to a period of 4 hours.;Time to analgesic requirement postoperativelyTimepoint: Pain & time to analgesic requirement will be monitored every 30 minutes after surgery upto a period of 4 hours.

Countries

India

Contacts

Public ContactNorin Qashifa

Sri Ramachandra Institute of Higher Education and Research

vjram2001@yahoo.co.in9841219820

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026