Comparing the effects and onset of action of two drugs in patients undergoing off pump coronary artery bypass graft surgery

Comparison of intubating conditions and hemodynamic effects between Rocuronium and Cisatracurium in patients undergoing off pump coronary artery bypass graft surgery :A randomized double blinded study - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080804

Enrollment

140

Registered

2025-02-18

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Cisatracurium group: Cisatracurium -0.15 mg /kg as a induction dose given as a bolus -intravenously (6 *ED 95) Control Intervention1: Rocuronium group: Rocuronium -1 mg/kg as a inductio

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anaesthesiologist(ASA) status 3

Exclusion criteria

Exclusion criteria: Patient refusal Inability to give consent to the study Coagulopathy, sepsis, hepatic or renal failure Allergic to Local Anaesthetic drugs Pre existing neuromuscular disorder Pregnant female Ejection fraction less than 40% ASA -4 and above

Design outcomes

Primary

Measure	Time frame
Onset of action Hemodynamic effects of Heart rate after tracheal intubation between two groupsTimepoint: Heart rate-baseline,at 1 minute,3 minute, 5 minute	—

Secondary

Measure	Time frame
Interpretation of TOF count for the onset of actionTimepoint: Baseline	—

Countries

India

Contacts

Public ContactDrSivalakshmi

SRI RAMACHANDRA MEDICAL COLLEGE AND RESEARCH INSTITUTE

Vakamudi@gmail.com9840022626

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026