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A comparative clinical study to see the changes in hemodynamic responses to laryngoscopy and intubation with the use of two induction agents

A COMPARATIVE STUDY OF HEMODYNAMIC RESPONSES TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION FOLLOWING INDUCTION WITH PROPOFOL VERSUS ETOMIDATE IN PATIENTS UNDERGOING MAJOR ABDOMINAL SURGERIES. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080780
Enrollment
100
Registered
2025-02-18
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Propofol: To compare the hemodynamic responses of propofol(2mg per kg body weight) intravenously at baseline, after induction of general anesthesia during laryngoscopy and intubation, a

Sponsors

Dr Muhsina Rahman
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients belonging to ASA grade 1-2 2. Patients belonging to age group 18-60 years. 3. Patients who are posted for elective major abdominal surgeries. 4.Patients who are willing to give informed written consent for surgery.

Exclusion criteria

Exclusion criteria: 1. Patients with known allergic history of the drugs of study. 2. Patients with known cardiovascular diseases. 3. Patients with any other co-morbid conditions. 4. Patients with anticipated difficult intubation

Design outcomes

Primary

MeasureTime frame
To compare the various hemodynamic responses in each group, namely - heart rate, systolic blood pressure, diastolic blood pressure, oxygen saturation.Timepoint: Before induction, after induction, during intubation, after 1,3,5 and 10 minutes post intubation

Secondary

MeasureTime frame
To compare the adverse effects (if any) of the drugs studied in each groupTimepoint: At baseline, after 1 minute of administration of drugs, after 5 minutes of administration of drugs, after 10 minutes of administration of drugs

Countries

India

Contacts

Public ContactDr Rajib Hazarika

Gauhati Medical College and Hospital

rajibhazarika8@gmail.com9864063140

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026