Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Minimum 20 year old patients with histopathological confirmation of Oral cancer and potentially premalignant lesions without any therapeutic interventions such as chemotherapy, radiotherapy, surgery or alternative remedies Similarly, age and gender matched healthy subjects without history of hypertension, diabetes, hypothyroidism or any medication use during last 3 months
Exclusion criteria
Exclusion criteria: Subjects with recurrent Oral Squamous Cell Carcinomas with metastasis in the head and neck region Conditions that causes Xerostomia/dry mouth
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To identify volatile organic compounds which can be used as salivary biomarkers for early diagnosis of oral malignant and premalignant lesionsTimepoint: 3 months- Saliva collection and analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| Transition from laboratory to chairside diagnostics- Development of a portable sensor based device with high sensitivity and specificity for rapid clinical diagnosis with great potential for next generation screening tool for oral cancer detection and managementTimepoint: 3 months- Scientific writing and article publication | — |
Countries
India