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A six month comparative evaluation of the healing of dental periapical lesions among various ABO blood group individuals A CBCT based observational study

A six month comparative evaluation of the healing of periapical lesions among various ABO blood group individuals A CBCT based observational study - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080734
Enrollment
48
Registered
2025-02-18
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z789- Other specified health status

Interventions

Intervention1: INDIVIDUALS WITH O POSITIVE BLOOD GROUPS: BLOOD GROUP O AMONG ABO BLOOD GROUPS AND RH POSITIVE TYPE are categorised under intervention as angelus bio-c sealer will be used for obturatio

Sponsors

Dr Riddhi Vasa
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Systemically healthy patients (Category: American Society of Anesthesiologists class 2 or less than 2) less than 45 years of age with maxillary or mandibular teeth diagnosed with symptomatic or asymptomatic apical periodontitis or acute exacerbation of chronic abscess will be included in the study. 2.Maxillary or mandibular single rooted teeth diagnosed with Pulpal necrosis with symptomatic or asymptomatic apical periodontitis with lesions that show periapical radiolucency with (CBCTPAI) Score 3 will be included in the study. 3.Re-treatment with periapical lesions with CBCTPAI Score 3 will be included in the study. 4.Patients who are aware of their respective blood groups will only be included in the study. 5.A written informed consent will be taken from all the patients and only those patients ready to sign the consent form will be included in the study.

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating women will be excluded. 2.Patients having uncontrolled diabetes, uncontrolled hypertension and immunocompromised will be excluded from the study. 3.Patients with history to any drug allergy will be excluded from the study. 4. Patients having teeth with poor prognosis, open apices, internal/external resorption, fractured roots or visibly cracked tooth, grade 3 mobility, severe periodontal bone loss will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
O POSITIVE INDIVIDUALS WILL SHOW BETTER PERIAPICAL HEALING AS COMPARED TO OTHER GROUPS DUE TO PRESENCE OF ANTI A- AND ANTI-B ANTIBODIESTimepoint: O POSITIVE INDIVIDUALS WILL SHOW BETTER PERIAPICAL HEALING AS COMPARED TO OTHER GROUPS DUE TO PRESENCE OF ANTI A- AND ANTI-B ANTIBODIES AS SEEN ON CBCT AT BASELINE(after 24 hrs AND after6 MONTHS)

Secondary

MeasureTime frame
O POSITIVE INDIVIDUALS WILL SHOW BETTER PERIAPICAL HEALING AS COMPARED TO OTHER GROUPS DUE TO PRESENCE OF ANTI A- AND ANTI-B ANTIBODIESTimepoint: O POSITIVE INDIVIDUALS WILL SHOW BETTER PERIAPICAL HEALING AS COMPARED TO OTHER GROUPS DUE TO PRESENCE OF ANTI A- AND ANTI-B ANTIBODIES after 6 months

Countries

India

Contacts

Public ContactDr Riddhi Vasa

K.M. SHAH DENTAL COLLEGE AND HOSPITAL

drajayinendo@gmail.com08385017307

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026