Health Condition 1: Z789- Other specified health status
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Systemically healthy patients (Category: American Society of Anesthesiologists class 2 or less than 2) less than 45 years of age with maxillary or mandibular teeth diagnosed with symptomatic or asymptomatic apical periodontitis or acute exacerbation of chronic abscess will be included in the study. 2.Maxillary or mandibular single rooted teeth diagnosed with Pulpal necrosis with symptomatic or asymptomatic apical periodontitis with lesions that show periapical radiolucency with (CBCTPAI) Score 3 will be included in the study. 3.Re-treatment with periapical lesions with CBCTPAI Score 3 will be included in the study. 4.Patients who are aware of their respective blood groups will only be included in the study. 5.A written informed consent will be taken from all the patients and only those patients ready to sign the consent form will be included in the study.
Exclusion criteria
Exclusion criteria: 1.Pregnant and lactating women will be excluded. 2.Patients having uncontrolled diabetes, uncontrolled hypertension and immunocompromised will be excluded from the study. 3.Patients with history to any drug allergy will be excluded from the study. 4. Patients having teeth with poor prognosis, open apices, internal/external resorption, fractured roots or visibly cracked tooth, grade 3 mobility, severe periodontal bone loss will be excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| O POSITIVE INDIVIDUALS WILL SHOW BETTER PERIAPICAL HEALING AS COMPARED TO OTHER GROUPS DUE TO PRESENCE OF ANTI A- AND ANTI-B ANTIBODIESTimepoint: O POSITIVE INDIVIDUALS WILL SHOW BETTER PERIAPICAL HEALING AS COMPARED TO OTHER GROUPS DUE TO PRESENCE OF ANTI A- AND ANTI-B ANTIBODIES AS SEEN ON CBCT AT BASELINE(after 24 hrs AND after6 MONTHS) | — |
Secondary
| Measure | Time frame |
|---|---|
| O POSITIVE INDIVIDUALS WILL SHOW BETTER PERIAPICAL HEALING AS COMPARED TO OTHER GROUPS DUE TO PRESENCE OF ANTI A- AND ANTI-B ANTIBODIESTimepoint: O POSITIVE INDIVIDUALS WILL SHOW BETTER PERIAPICAL HEALING AS COMPARED TO OTHER GROUPS DUE TO PRESENCE OF ANTI A- AND ANTI-B ANTIBODIES after 6 months | — |
Countries
India
Contacts
K.M. SHAH DENTAL COLLEGE AND HOSPITAL