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Effect of two differnt drugs in management of acute bronchial asthma

Nebulized levosalbutamol versus combination of magnesium sulphate and levosalbutamol nebulization in acute bronchial asthma - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080682
Enrollment
70
Registered
2025-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J459- Other and unspecified asthma

Interventions

Intervention1: Nebulisation in acute bronchial asthma Intervention -Group B nebulised with magnesium sulphate and levosalbutamol Comparator agent-Group A nebulised with levosalbutamol. : Group B is ne

Sponsors

Shyam Shah medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients newly diagnosed or known cases of bronchial asthma,aged 2-15 years are Nebulized bronchodilator which will be levosalbutamol in group (A) in the form of 4 doses of nebulized solution 0.5 gm% (each dose 1 ml containing 5 mg levosalbutamol) twenty minutes apart and magnesium sulphate in group (B) in the form of 2 doses of nebulized solution 10 gm% (each dose 1 ml containing 100 mg magnesium sulphate) twenty minutes apart with 4 doses of nebulized solution 0.5 gm percent (each dose 1ml containing 5 mg levosalbutamol) twenty minutes apart Reassessment of the patients will be performed after 2 hours to detect improvement.

Exclusion criteria

Exclusion criteria: 1.Fever 2.Smoker 3.COPD patients 4.Pneumonia 5.Cardiac,renal or hepatic insufficiency 6.Respiratory failure

Design outcomes

Primary

MeasureTime frame
Reassessment of vitals heart rate,respiratory rate,saturation,Glass Gow Coma scale and peak expiratory flow metre at baseline and after 2 hours.Timepoint: Reassessment of vitals heart rate,respiratory rate,saturation,Glass Gow Coma scale and peak expiratory flow metre at baseline and after 2 hours.

Secondary

MeasureTime frame
Duration of stay in intensive care unit. Duration of hospital stayTimepoint: Duration of stay in intensive care unit Duration of hospital stay

Countries

India

Contacts

Public ContactDr Shabd Singh Yadav

Shyam Shah medical college

Sshabd@yahoo.com9827260904

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026