Health Condition 1: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: Receiving ondansetron (Group A): Subjects will be administered with 4mg ondansetron (2ml) stat intraperitoneally in the gall bladder bed via irrigation at the end of procedure.
Control
Sponsors
Mohd Sharib Wahaj
Eligibility
Inclusion criteria
Inclusion criteria: All patients more than 18 years planned for laparoscopic and robotic cholecystectomy.
Exclusion criteria
Exclusion criteria: 1.Patients who have liver or renal dysfunction. 2.Patients who have chronic pain other than symptomatic cholelithiasis. 3.Patients who have history of daily intake of corticosteroids or a history of allergy to any of the study drugs. 4.Patients with communication problems, cognitive dysfunction, or psychological disorders. 5.Patients who received analgesics or sedatives 24 h before a scheduled surgery. 6.All pregnant/lactating females 7.Patients undergoing concomitant surgeries 8.Minimally invasive procedure converted to open procedure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the efficacy in pain relief from baseline to 12, and 24 hours post-operatively in the study populationTimepoint: To evaluate the efficacy in pain relief from baseline to 12, and 24 hours post-operatively in the study population | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the differences between study groups in Time to first rescue analgesic request Cumulative consumption of rescue analgesic postoperative period till discharge. Time for unassisted mobilization. Timepoint: Cumulative dose of rescue analgesia required in 24 hours, time to first recue analgesia request and time to unassisted mobilization. | — |
Countries
India
Contacts
Public ContactDr Vikram Kate
Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Pondicherry
Outcome results
None listed