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Comparison of the Antimicrobial effect of three herbal irrigants in primary endodontic infections

Comparitive Evaluation of The Antimicrobial Efficacy of Three Herbal Irrigants in Primary Endodontic Infections- A Randomized Clinical Trial - Nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080671
Enrollment
60
Registered
2025-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Chitosan: Pretreatment Sample will be obtained by injecting normal saline (5 ml) into the root canal and circumferentially pumping a #15 K-file. A sterile paper point will be inserted a

Sponsors

SGT University
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient aged 25-65 years. Single rooted teeth with one canal. Single rooted teeth with symptomatic apical periodontitis. Single rooted teeth with irreversible pulpitis. Teeth with necrotic pulp that will be confirmed by pulp sensitivity test. No previous history of endodontic treatment Tooth should have enough coronal tooth structure for rubber dam placement.

Exclusion criteria

Exclusion criteria: Teeth with unrestorable tooth structure Patients with poor periodontal status.(periodontal pockets 5 mm) Patients with sinus tract, periapical abscess or intraoral swelling. Retreatment cases Presence of a difficult root canal anatomy such as dilaceration, calcified canals, immature apex, root resorption. Patients who had received nsaids or antibiotic treatment in three months before the study.

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the antibacterial effectiveness of three herbal irrigants, propolis, chitosan and curcumin with sodium hypochlorite in the primary endodontic infections treated in two visit endodontic treatment. Timepoint: Pre operative and immediately after irrigation

Secondary

MeasureTime frame
To evaluate & compare the antibacterial efficacy of the three herbal irrigants propolis, chitosan & curcumin with sodium hypochlorite, in the primary endodontic infections treated in two visit endodontic treatment. Timepoint: Pre operative & immediately after irrigation

Countries

India

Contacts

Public ContactDr.Ankita Sharma

SGT Dental College,Hospital and Research Institute

as.ankita06@gmail.com9682575180

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026