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A study to explore the role of zinc supplementation in hypertensive patients with antihypertensive drugs.

A prospective study to evaluate the effects of zinc supplementation as an add on therapy with antihypertensive drugs in patients suffering from stage 1 and stage 2 hypertension. - Nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080669
Enrollment
140
Registered
2025-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I119- Hypertensive heart disease withoutheart failure

Interventions

Intervention1: Zinc Sulphate with antihypertensive drugs.: Tablet Zinc sulphate 20 mg will be administered orally , once a day along with antihypertensive drug for a period of 12 weeks in hypertensive

Sponsors

Department of pharmacology Government medical college Patiala
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Individuals having systolic blood pressure of 140-179mmHg and diastolic blood pressure of 90-109mmHg. 2. Should be able to meet follow up requirements for minimum of 12 weeks.

Exclusion criteria

Exclusion criteria: 1. Children, Pregnant and lactating women. 2. Acute and seriously ill patients such as liver cirrhosis, sepsis, chronic kidney disease etc. 3. Patients suffering from severe cardiovascular conditions such as congestive heart failure, patients with systolic blood pressure of 180 mm Hg and higher , and diastolic blood pressure of 110 mmHg and higher. 4. Patients allergic to zinc supplements. 5. History of malignancy. 6. Patients unable to meet the follow up requirements of 12 weeks.

Design outcomes

Primary

MeasureTime frame
Effective and timely reduction of both systolic and diastolic blood pressure with zinc supplementation along with anti hypertensive drugs in hypertensive patients in comparison to the group only recieving antihypertensive drugs.Timepoint: 1 year

Secondary

MeasureTime frame
Evaluating the adverse effects of zinc supplementation along with antihypertensive drugs in hypertensive patients.Timepoint: 1 year.

Countries

India

Contacts

Public ContactAjink vasudev pawar

Government medical college and rajindra hospital

anjleen9@gmail.com9855210999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026