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A RANDOMIZED CONTROLLED TRIAL COMPARING EFFECTS ON BLOOD PRESSURE OF PREGNANT PATIENTS UNDERGOING C-SECTION AND ON BLOOD PH ON NEWBORN NEONATES AFTER ADMINISTRATION OF INJECTION EPHEDRINE AND PHENYLEPHRINE DURING SPINAL ANAESTHESIA FOR C-SECTION

A RANDOMIZED CONTROLLED TRIAL COMPARING MATERNAL AND NEONATAL EFFECTS OF BOLUS ADMINISTRATION OF EPHEDRINE AND PHENYLEPHRINE DURING SPINAL ANAESTHESIA FOR CAESAREAN SECTION - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080642
Enrollment
56
Registered
2025-02-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: Epinephrine 6mg bolus and Phenylephrine 100mcg bolus: Every patient posted for Caeserean section surgery will be selected based on selection criteria and randomly divided into two group

Sponsors

Bharati Hospital and Research Centre
Lead Sponsor
Bharati Hospital and Research centre
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients undergoing elective lower segment caesarean section 2)American Society of Anaesthesiologists (ASA) Grade II

Exclusion criteria

Exclusion criteria: 1)Patients not willing to participate in the study 2)Patients with pre-existing or pregnancy-induced hypertension, diabetes mellitus, known cardiovascular or cerebrovascular disease. 3)Patients with fetal abnormalities. 4)Patients indicated for LSCS i/v/o fetal distress. 5)Patients with any known hypersensitivity to any of the study drug. 6)Patients contraindicated to central neuraxial blocks

Design outcomes

Primary

MeasureTime frame
To compare the effect on neonatal cord blood PH after the administration of bolus doses of Ephedrine and Phenylephrine.Timepoint: Intraoperative duration—

Secondary

MeasureTime frame
1)To compare maternal blood pressure and heart rate with administration of bolus doses of Ephedrine and Phenylephrine. 2)To compare effects on neonatal cord blood glucose levels after administration of bolus doses of Ephedrine and Phenylephrine. Timepoint: Intraoperative duration—

Countries

India

Contacts

Public ContactDr. Rutwij Raut

Bharati Vidyapeeth Deemed to be University Medical College

varshkeniya@yahoo.com9881419089

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026