comparision of lung parameters using ultrasound and chest xray in patients recieving terlipressin and noradrenaline in participants with kidney injury in liver disease patients.

Comparison of Terlipressin vs Noradrenaline Through Assessment of Respiratory Parameters, Lung Ultrasound Scores, and RALES Score in Patients With Hepatorenal Syndrome A Comparative Randomized Controlled Study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080614

Enrollment

100

Registered

2025-02-14

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K746- Other and unspecified cirrhosis ofliver

Interventions

Intervention1: Terlipressin + Albumin: Terlipressin 1 mg q12h and Albumin 20g in 100ml once a day until clinical improvement or maximum of 14 days Control Intervention1: Noradrenaline: minimum dose o

Eligibility

Inclusion criteria

Inclusion criteria: Patients admitted to the critical care unit diagnosed as hepatorenal syndrome on treatment with terlipressin or noradrenaline plus albumin.

Exclusion criteria

Exclusion criteria: Patients not willing for ultrasound examination. Improvement in renal function after central blood volume expansion History of infection within the past week, excluding spontaneous bacterial peritonitis; History of coronary artery disease, obstructive cardiomyopathy, ventricular arrhythmia, or obliterative arterial disease of the limbs

Design outcomes

Primary

Measure	Time frame
To assess respiratory parameters and venous congestion in patients with hepatorenal syndrome being treated with noradrenaline and terlipressin plus albumin through ultrasound and rales score and its association with various outcomes in intensive care stay.Timepoint: DAY 1 TO 15	—

Secondary

Measure	Time frame
To determine how measurement of venous congestion and assessment of respiratory parameters using ultrasound and rales score in patients of hepatorenal syndrome on terlipressin or noradrenaline plus albumin helps in evaluation of fluid overload and its impact on clinical, demographic and biochemical variables.Timepoint: Day 1 to 15	—

Countries

India

Contacts

Public ContactVedaghosh Amara

AIG Hospitals

vedaghosh@gmail.com9985087798

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026