A study to compare the motor weakness caused and ability to walk between 2 drugs used for spinal anaesthesia, 0.75% ropivacaine heavy and 0.5% bupivacaine heavy for surgeries in below the umbilicus

TO COMPARE THE EFFICACY OF HYPERBARIC ROPIVACAINE 0.75% VS HYPERBARIC BUPIVACAINE 0.5% ON MOTOR RECOVERY AND POSTOPERATIVE AMBULATION AFTER SPINAL ANAESTHESIA IN INFRAUMBILLICAL SURGERIES - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080579

Enrollment

Registered

2025-02-14

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: 0.75% hyperbaric ropivacaine: 3ml of 0.75% ropivacaine heavy ( 22.5mg) given once in subarachnoid space with patient in sitting position with a 25G quincke needle at a speed of 0.2ml/se

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient willing to give informed consent 2. ASA grade 1 and 2 3. Patients undergoing infraumbilical surgeries under spinal anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients refusing to give informed consent 2. Patients undergoing emergency surgeries 3. Patients with history of allergy to the study drugs 4. Pregnant women 5. Patients ASA grade 3,4,5 6. Patients under 18 years and over 60 years of age. 7. Infection at the site of injection 8. Sepsis 9. Spinal deformities 10. Severe hypovolemia 11. Coagulopathies 12. Raised intracranial tension

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of hyperbaric ropivacaine 0.75% with hyperbaric bupivacaine 0.5% on motor recovery and post operative ambulationTimepoint: baseline, 1, 2, 3, 4, 5, 6, 7. 8, 9, 10 mins, 20, 30, 40, 50, 60, 70, 80, 90 minutes. every 30 minutes till patient able to ambulate	—

Secondary

Measure	Time frame
To compare the effects of the 2 drugs on heart rate, systolic blood pressure, diastolic blood pressure, mean arterial pressure, saturation of oxygen & the incidence of adverse effects if any.Timepoint: aseline, every minute upto 10 minutes, every 10 minutes upto end of surgery	—

Countries

India

Contacts

Public ContactDr Vinay Marulasiddappa

Bangalore Medical College and Research Institute

drvinaym@gmail.com8073997005

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026