"How Gum Disease Treatment Affects Inflammation in Diabetic and Non-Diabetic Patients"

Effect of Non-surgical periodontal treatment (NSPT) on the IL-20 levels in Periodontitis patients with and without Diabetes Mellitus (Type 2) : A Clinico-Biochemical Study - NIL

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080538

Enrollment

Registered

2025-02-13

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: Non-Surgical Periodontal Treatment (NSPT): Non-Surgical Periodontal Treatment (NSPT) typically involves scaling and root planing (SRP) in diabetic patients to remove plaque and calculus

Eligibility

Inclusion criteria

Inclusion criteria: 1. Both men and women of 35 to 55 years of age. 2. Presence of at least 20 teeth in the oral cavity. 3. Patients belonging to Chhattisgarh state. 4. Patient willing to undergo periodontal treatment procedure.

Exclusion criteria

Exclusion criteria: 1. Participants with any known systemic disease other than diabetes mellitus (type 2). 2. History of smoking or any other form of tobacco use, alcohol intake and drug abuse will be excluded from the study. 3. Pregnant women or lactating women. 4. History of any form of periodontal treatment in the past 3 months. 5. Patients who used antibiotics or other drugs that affect periodontal status in the past 3 months.

Design outcomes

Primary

Measure	Time frame
The study will help us to correlate between variation in Interleukin-20 levels in periodontitis patients with and without diabetic mellitus (type 2).Timepoint: Baseline, 6 weeks, 12 weeks	—

Secondary

Measure	Time frame
Secondary outcome of the study of the study is that non surgical periodontal treatment (NSPT) will have significant impact on Interleukin-20 levels and will be well correlated with clinical parameters of periodontal tissue destruction and glycemic status.Timepoint: 18 months	—

Countries

India

Contacts

Public ContactDr Manisha Kumari

Government Dental College, Raipur C.G

vinleo76@gmail.com8168649948

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026