Health Condition 1: L80- Vitiligo
Conditions
Interventions
Intervention1: oral drugs: oral drugs i.e. oral tofacitinib and oral azathioprine will be given in group A and B respectively for 12 weeks
Control Intervention1: Oral tofacitinib(Group A ) : Patients
Sponsors
Dr Aishwarya Acharya
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with clinical signs of unstable vitiligo 2.Patients who have not taken any systemic treatment in last 1 month , topical treatment in last 2 weeks and excimer laser in last 8 weeks 3. When body surface area more than 10% involved 5.Patient willing to participate in the study
Exclusion criteria
Exclusion criteria: 1.Patient with exclusive segmental and mucosal vitiligo 2. Pregnancy and lactation 3. Patients with active TB infection or any contact with TB patient 4. Patients with chronic liver disease , cirrhosis, HIV/AIDS, renal dysfunction , malignancies 5.Patients on drugs interacting with azathioprine / tofacitinib 6.Patient with history of hypersensitivity to tofacitinib / azathioprine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the efficacy of oral tofacitinib and oral azathioprine in unstable vitiligoTimepoint: one year | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the safety of oral tofacitinib & oral azathioprine in unstable vitiligoTimepoint: One year | — |
Countries
India
Contacts
Public ContactDr Aishwarya Acharya
Jawaharlal Nehru Medical College, Belgavi-590010
Outcome results
None listed