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Asssessment of Bromelain gel in treatment of Gum diseases.

Evaluation of clinical efficacy of locally delivered novel composite gel containing Bromelain as an adjunct to non surgical periodontal therapy - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080514
Enrollment
60
Registered
2025-02-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Novel Composite gel containing Bromelain: After baseline examination the test sites will be treated with SRP followed by subgingival administration of novel composite gel containing Bro

Sponsors

Ranjeet Deshmukh Dental College and Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Systemically healthy patients within the age group of 18 65 years. 2. Patients should have at least 14 natural teeth in the oral cavity. 3. Patients with no history of allergies. 4. Patients who are diagnosed with generalized periodontitis of stages II and III (According to World Workshop of Periodontology, 2017 with bilateral periodontal pockets with probing pocket depth of between 4 and 6 mm.

Exclusion criteria

Exclusion criteria: 1. Smokers. 2. Pregnant and lactating mothers. 3. Patients who received radiotherapy, chemotherapy or immunosuppressive treatment, systemic corticosteroids, and/or anticoagulants 30 days prior to intervention. 4. Patients with any systemic disease. 5. Patients under the influence of non-steroidal anti-inflammatory drugs (NSAIDS) or any other anti-inflammatory medications, antibiotics, steroids that can alter the course of periodontitis progression and treatment.

Design outcomes

Secondary

MeasureTime frame
Patient reported Outcome measures will be assessedTimepoint: baseline, 3 months and 6 months

Primary

MeasureTime frame
Probing Pocket DepthTimepoint: baseline, 3 months and 6 months

Countries

India

Contacts

Public ContactDR PRANJALI BAWANKAR

Ranjeet Deshmukh Dental College and Research Centre, Nagpur

drpranjalibawankar@gmail.com9975128729

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026