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A clinical trial to comparatively study 0.5 percentage hyperbaric levobupivacaine, 0.75 percentage hyperbaric ropivacaine and 0.5 percentage hyperbaric bupivacaine with fentanyl in subarachnoid block for lower limb surgeries.

Comparative study of 0.5 percentage hyperbaric levobupivacaine, 0.75 percentage hyperbaric ropivacaine and 0.5 percentage hyperbaric bupivacaine with fentanyl in subarachnoid block for lower limb surgeries. - Nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080510
Enrollment
200
Registered
2025-02-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S00-T88- Injury, poisoning and certain other consequences of external causes

Interventions

Intervention1: Comparative study of 0.5% hyperbaric levobupivacaine, 0.75% hyperbaric ropivacaine and 0.5% hyperbaric bupivacaine with fentanyl in subarachnoid block for lower limb surgeries.: Patient

Sponsors

Dayanand Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists (ASA) gradeI, II and III.

Exclusion criteria

Exclusion criteria: 1. Patient refusal for subarachnoid block. 2. Patients with allergy to local anaesthetic drugs or any history of anaphylacticreaction to the drugs used. 3. Patients with coagulopathy evidenced by history and laboratory investigations. 4. Patients with infection at injection site 5. Patients with spinal deformities like kyphoscoliosis and scoliosis etc. 6. Patients with history of pre-existing neurological disease. 7. Unable to comprehend sensory and motor block. 8. Patient’s refusal for consent. 9. Patients with failed spinal anaesthesia and subsequent conversion to general anaesthesia.

Design outcomes

Primary

MeasureTime frame
Onset of sensory and motor blockTimepoint: 0 min, 2min, 4min, 6min, 8min , 10min ,15min and thereafter every 15min till two dermatome regression from maximum level of sensory block occurs

Secondary

MeasureTime frame
1.To determine highest level and duration of sensory block. 2. Duration of motor block Timepoint:

Countries

India

Contacts

Public ContactDr Japneet Bakhshi

Dayanand Medical College and Hospital

bakhshijapneet@gmail.com9501444357

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026