Health Condition 1: D898- Other specified disorders involving the immune mechanism, not elsewhere classified
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: NIL: NIL
Control Intervention2: NIL: NIL
Sponsors
Aster CMI Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age above 18 at the time of informed consent. 2.Willing to give Informed consent 3.Confirmed diagnosis of CRC for which no treatment was initiated
Exclusion criteria
Exclusion criteria: 1.unwilling to consent 2.usage of antibiotics, antivirals, anti parasitic agents in the last 3 months 3) usage of immunosuppressive medications 3 months 4) Major surgery to the gastrointestinal tract in the previous 5 years 5) usage of probiotics greater than 1000000000 cfu per day in the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) To analyse the prevalent gut microbiome in the Indian CRC patients and compare it to the data from the non CRC or healthy cohort 2) To observe the change in the microbiome post definitive anti-cancer treatmentTimepoint: DNA sequencing of the gut microbiome at 2 time points. Baseline and 6 Months post treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| To observe the change in the microbiome post definitive anticancer treatmentTimepoint: Two time points 1. Baseline 2. 6 months post treatment | — |
Countries
India
Contacts
Public ContactDr Surinder Kher
Aster CMI Hospital
Outcome results
None listed