THERAPEUTIC DRUG MONITORING OF ANTIMICROBIALS IN CRITICALLY ILL PATIENTS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY IN CRITICALLY ILL PATIENTS

THERAPEUTIC DRUG MONITORING OF ANTIMICROBIALS BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY IN CRITICALLY ILL PATIENTS - TDM by HPLC

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080503

Enrollment

100

Registered

2025-02-13

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z71- Persons encountering health services for other counseling and medical advice, not elsewhere classified

Interventions

Intervention1: Blood analysis: Venous blood sample of 2ml will be collected in heparinized tube, mixed and stored in ice box will be transferred to central research lab. Control Intervention1: NOT APP

Eligibility

Inclusion criteria

Inclusion criteria: ICU patients Started on fresh IV antibiotics after test dose

Exclusion criteria

Exclusion criteria: Patients on oral antimicrobials Patients with TB/HIV Sudden switch over to antibiotics without washout period

Design outcomes

Primary

Measure	Time frame
to estimate the Plasma concentration of the administered drugTimepoint: 30 mins post drug administration trough level	—

Secondary

Measure	Time frame
To look for Drug toxicity in plasma concentrationTimepoint: at the time of sample analysis by HPLC	—

Countries

India

Contacts

Public ContactDr Abdul Rasheed Razia

Melmaruvathur Adhiparasakthi institue of medical sciences and research

dr.raziaar@gmail.com8220535495

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026