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Comparison of peri-implant bone levels and tgf-alpha levels in peri-implant crevicular fluid in immediate vs delayed implant placement

Comparative evaluation of immediate versus delayed loading on peri-implant bone levels and tgf-alpha levels in peri-implant crevicular fluid - A clinico-biochemical study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080479
Enrollment
16
Registered
2025-02-13
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: immediete loading: immediete loading done after placement of implant followed by record keeping. frequency : once total duration : three months Control Intervention1: delayed laoding: d

Sponsors

SHREYA MISHRA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Subjects aged above 18 years requiring Implant placement. 2. Patients with adequate oral hygiene status 3. No active periodontal disease 4. Sufficient bone quality (D1, D2 and D3) and quantity 5. Proper inter-occlusal space in missing tooth region 6. Patients who are willing to comply with the treatment protocol 7. Extraction must be done at least 3 months prior to treatment

Exclusion criteria

Exclusion criteria: 1. Patients with uncontrolled diabetes. 2. Patients with autoimmune diseases, psychiatric disorders, osteoporosis 3. Patients undergoing or who underwent radiation therapy and chemotherapy to the head and neck region during the last 12 months 4. Patients with poor oral hygiene 5. Alcoholic, drug abusers and heavy smokers 6. Pregnant and lactating women 7. Sites with acute infection

Design outcomes

Primary

MeasureTime frame
To evaluate and compare levels of TGF alpha in PICF around immediate and delayed loaded implants at 15 days, 1 month and at 3 months and to evaluate and compare the marginal bone loss at baseline to 3 monthsTimepoint: Baseline- 3 months

Secondary

MeasureTime frame
Comparision of bleeding on probing and ISQ measurements between immediate and delayed loaded implants at baseline and 3 months.Timepoint: Baseline- 3 months

Countries

India

Contacts

Public ContactSHREYA MISHRA

ITS DENTAL COLLEGE

shreyamishra_mds22_25@its.edu.in8095059908

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026