Health Condition 1: L439- Lichen planus, unspecified
Conditions
Interventions
Intervention1: Topical Roflumilast 0.3%: Topical application of Roflumilast 0.3% in symptomatic Oral Lichen Planus patients with followup on baseline, 1,2 and 3 months.
Control Intervention1: Topical
Sponsors
KRITIKA TIWARI
Eligibility
Inclusion criteria
Inclusion criteria: Participants of both gender and age between 18 years to 60 years, will be diagnosed with symptomatic lesions of reticular, atrophic, and erosive oral lichen planus based on clinical, histopathological criteria by WHO. Patients who give informed consent after explaining the treatment type will be included in the study.
Exclusion criteria
Exclusion criteria: Patients with any other Potentially Malignant Oral Disorders (PMOD) will be excluded. Pregnant females and breastfeeding mothers will be excluded. Patients with a history of corticosteroids, NSAIDs, or any other treatment in the last 30 days will be excluded. Treatment with any drug or restoration that may include lichenoid reaction. Patients with other systemic diseases or illnesses will be excluded. Patient allergic to stated medication will also be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| appearance of normal mucosa (Score 2 on Thongprasom scale),pain and Burning sensation (VAS 3).Timepoint: Baseline, 1 month, 2 months, 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| normal mucosa (Score 0),absence of pain and BS (VAS 0)Timepoint: Baseline, 1 month, 2 months, 3 months | — |
Countries
India
Contacts
Public ContactDr Adit
Institute of Medical Sciences, Banaras Hindu University
Outcome results
None listed