Health Condition 1: - Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Inj. Fentanyl 2 mcg/kg & Inj. Clonidine 2 mcg/kg: Inj. Fentanyl 2 mcg/kg & Inj. Clonidine 2 mcg/kg Given 3 minutes prior to laryngoscopy & Endotracheal Intubation
Control Intervention1:
Sponsors
Smt. Bhikhiben Kanjibhai Shah Medical Institute and research centre
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patients willing to sign informed consent 2) Male or Female patients between 18 to 60 years of age 3) Patients belonging to American Society of Anaesthesiologists(ASA) physical status I, II, & III 4) Patients posted for elective cardiovascular surgeries under general anaesthesia. 5) Patients with ejection fraction more than or equal to 40%
Exclusion criteria
Exclusion criteria: 1) Patients unwilling to participate in the study 2) Patients with Body Mass Index more 29 kg per meter square 3) Patients with cerebrovascular diseases, hepatic and/or renal diseases 4) Psychiatric patients 5) Pregnancy and lactating women 6) Patients belonging to American Society of Anaesthesiologists (ASA) 4 and above. 7) Patients with ejection fraction less than 40%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study Haemodynamic response during Laryngoscopy & endotracheal intubationTimepoint: 1) At baseline 2) After test drug administration 3) After Induction 4) At Laryngoscopy and Endotracheal intubation 5) After intubation at 1st, 3rd, 5th and 7th minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| To study Sedation Score after extubation or any side effectsTimepoint: 1) Immediately after extubation 2) Every 5 minutes after extubation till the completion of 30 minutes 3) Then every 30 minutes till the completion of 2 hours. | — |
Countries
India
Contacts
Public ContactDr Kalpesh Patil
Smt. Bhikhiben Kanjibhai Medical Institute and research centre
Outcome results
None listed