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Evaluating the Effect of Dexmedetomidine on Blood Pressure During Minimally Invasive Laparoscopic Surgery

To evaluate the effectiveness of intravenous dexmedetomidine infusion on intraoperative hemodynamics during laparoscopic surgery : A prospective randomised study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080428
Enrollment
98
Registered
2025-02-12
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group D (Dexmedetomedine group): Patients will receive dexmedetomedine infusion (loading: 0.5 microgram per kilogram and maintenance: 0.2 microgram per kilogram per hour by intravenous

Sponsors

JLN medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -Patients aged 18-60 years of either sex -Body weight 40-80 kilogram -ASA Grade first and second -Patients scheduled for laproscopic surgery and who are willing to give written and informed consent for general anaesthesia.

Exclusion criteria

Exclusion criteria: 1. Age less then 18 years and more then 60 years 2. ASA grade third and fourth 3. Patients not willing to participate in the study 4. Patients with a history of drug allergy 5. Patients with chronic pre-existing disease like Asthma, Renal or Hepatic dysfunction, diabetes mellitus, neuro muscular diseases, severe respiratory diseases etc. 6. Pregnancy/Lactation.

Design outcomes

Primary

MeasureTime frame
Effectiveness of perioperative iv dexmetadomidine on haemodynamicTimepoint: Baseline

Secondary

MeasureTime frame
1. Pressor response due to laryngoscopy 2. Smooth extubation with maintaing haemodynamic stability 3. Side effects if any like hypotension, bradycardia, sedation & various other side effects post operatively.Timepoint: Baseline to 90 min after induction of anaesthesia

Countries

India

Contacts

Public ContactDr Veena Patodi

JLN medical college and hospital

veenapatodi@gmail.com9414008276

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026