Health Condition 1: N186- End stage renal disease
Conditions
Interventions
Intervention1: 70 % Ethanol: Patients in the experimental arm will receive weekly catheter instillation of intravenous-grade 70% ethanol for 48 hours (for patients on thrice weekly hemodialysis) and 7
Sponsors
Dr Vishal Mangal
Eligibility
Inclusion criteria
Inclusion criteria: Incident and prevalent hemodialysis patients with tunnelled jugular venous catheters who are hemodynamically stable. Patients on twice weekly or thrice weekly hemodialysis Able to give informed consent No documented catheter-related bloodstream infection or exit site infection ever after catheter insertion in last three months
Exclusion criteria
Exclusion criteria: 1. Personal, cultural, or other objections to the use of alcohol as a catheter lock 2. Patients of femoral/subclavian tunneled catheters 3. Intolerance to alcohol 4. Patients on disulfiram 5. Pregnant/ breastfeeding patients 6. History of exit site infection or CRBSI associated with the current catheter in the last three months before inclusion into the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Time to first episode of CRBSITimepoint: follow up of 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Time to exit site infection 2. Time to infection-related catheter removal 3. Safety and tolerance profile of alcohol like dizziness, headache, vomiting and derangement of liver enzymes will be studied. 4. Catheter dysfunction Timepoint: Participants will be followed upto 8 weeks | — |
Countries
India
Contacts
Public ContactDr Vishal Mangal
Post Graduate Institute of Medical Education And Research
Outcome results
None listed