Health Condition 1: J211- Acute bronchiolitis due to human metapneumovirus Health Condition 2: J218- Acute bronchiolitis due to other specified organisms Health Condition 3: J210- Acute bronchiolitis due to respiratory syncytial virus Health Condition 4: J219- Acute bronchiolitis, unspecified
Conditions
Interventions
Intervention1: Heated Humidified High Flow Nasal Cannula (HHHFNC) driven nebulization: HFNC-driven nebulization using jet nebuliser (connected to the HFNC through a T channel) with recommended aerosol
Sponsors
Manikandan Arunasalam Kasi
Eligibility
Inclusion criteria
Inclusion criteria: Infants and young children aged 0-2 years with bronchiolitis diagnosed clinically by physician supported by X-ray and laboratory investigations will be included.
Exclusion criteria
Exclusion criteria: Any patients requiring immediate respiratory support (non-invasive or invasive mechanical ventilation), altered mental status, or apnoea at presentation), those already admitted to the ICU due to respiratory failure, those with underlying chronic lung disease or cardiovascular disorders, those with obstructions of the upper respiratory tract, and those with cranial malformations will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in respiratory distress scores from baseline. (Downes score) Timepoint: Duration of study : 12 to 18 months No specified frequency, continued throughout the course of the individual treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Need for Escalation of respiratory support. Timepoint: 12 to 18 months;Duration of hospital stay. Timepoint: 12 to 18 months;Adverse events related to the nebulization technique.Timepoint: 12 to 18 months | — |
Countries
India
Contacts
Public ContactDr Alexander
Department of Paediatrics, Chettinad Hospital and Research Institute
Outcome results
None listed