Topical Ripasudil in patients with corneal edema post-cataract surgery

Role of Ripasudil in faster resolution of corneal edema in patients post cataract surgery - NIL

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080364

Enrollment

Registered

2025-02-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H181- Bullous keratopathy

Interventions

Intervention1: ripasudil eyedrops 0.4%: Ripasudil eyedrops will be instilled twice a day for 2weeks Control Intervention1: hypertonic saline 5%: instilled twice a day for 2 weeks.

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing cataract surgery- Phacoemulsification and small incision cataract surgery with any grade of corneal edema on post-operative Day 1

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To evaluate the potential of Ripasudil 0.4% in resolution of corneal edema postoperatively, to obtain corneal transparency.Timepoint: every subject is followed up at the end of 1st week, 2nd week and 6th week	—

Secondary

Measure	Time frame
Compare the efficacy of ripasudil versus standard of care in treatment of postoperative corneal edemaTimepoint: all participants of the trial are followed up over 6 weeks	—

Countries

India

Contacts

Public ContactShubashree Karat

St Johns Medical College and Hospital

shubashree.karat@gmail.com09900325184

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026