A comparison of epicardial and endocardial suture occlusion surgical techniques for left atrial appendage in patients undergoing mitral valve surgery: A pilot prospective randomized comparative study

A comparison of epicardial and endocardial suture occlusion surgical techniques for left atrial appendage occlusion in patients undergoing mitral valve surgery: A pilot prospective randomized comparative study - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080341

Enrollment

100

Registered

2025-02-12

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Left atrial appendage surgical occlusion: Left atrial appendage surgical occlusion epicardial v/s endocardial in patients undergoing mitral valve surgery with or without concomitant tri

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing mitral valve surgery with or without tricuspid valve surgery above the age of 18 years to 80 years are included

Exclusion criteria

Exclusion criteria: Redo Surgery including closed mitral valvotomy Recent onset cardio-embolic stroke Less than six weeks Patients requiring concomitant surgical intervention for critical coronary, carotid artery disease. • Coagulopathy • Emergency Surgery • Refusal to participate in the study

Design outcomes

Primary

Measure	Time frame
to study efficacy of two surgical techniques in complete occlusion of left atrial appendage: epicardial and endocardial occlusion suture occlusion in patients undergoing mitral valve surgeryTimepoint: to study efficacy of two surgical techniques in complete occlusion of left atrial appendage: epicardial and endocardial occlusion suture occlusion in patients undergoing mitral valve surgery	—

Secondary

Measure	Time frame
to compare incidence of cardioembolic stroke in patients of both groups to compare outcomes in incidence of postoperative complications: reoperation for bleeding, acute renal failure, respiratory failure, cerebrovascular accidents, mortalityTimepoint: total 1 year follow up	—

Countries

India

Contacts

Public ContactDeepak Sharma

All India Institute of Medical Sciences, Rishikesh

danishaiims77@gmail.com9873433256

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026