A clinical trial to study the effects of volume controlled ventilation versus pressure controlled ventilation on respiratory functions and duration of ventilatory requirement with severe pulmonary arterial hypertension postoperatively posted for intrathoracic repairs

Effects of volume-controlled ventilation versus pressure controlled ventilation on perioperative respiratory functions and postoperative ventilator requirement, in patients posted for intracardiac repair for congenital heart diseases with severe PAH. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080319

Enrollment

Registered

2025-02-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I288- Other diseases of pulmonary vessels

Interventions

Intervention1: Volume controlled ventilation: In patients with congenital heart disease with severe PAH respiratory rate will be adjusted to maintain an end tidal carbon dioxide in the range of 30-35m

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with severe PAH Patients slated to undergo intrathoracic surgeries. Patients who provide valid informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Patients with mild to moderate PAH, Patients with pre-existing lung disorders, Patients with severe diseases of the cardiovascular, respiratory, and neurological systems. Patients with low left ventricular ejection fraction, Patients with impaired renal and hepatic parameters, Patients posted for emergency procedures Patients who will require one-lung ventilation for the procedures Patients not giving a valid consent to participate in the study.

Design outcomes

Primary

Measure	Time frame
Effects of Volume-Controlled Ventilation Versus Pressure Controlled Ventilation on Respiratory Functions and Duration of Ventilatory Requirement, Postoperatively, in Patients with Severe PAH, Posted for Intrathoracic RepairsTimepoint: 72 hours	—

Secondary

Measure	Time frame
NILTimepoint: NA	—

Countries

India

Contacts

Public ContactDr Sharayu Paunikar

Acharya Vinobha Bhave Rural Hospital, JMNC

drvivekchakole@rediffmail.com7583836564

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026