Health Condition 1: T424- Poisoning by, adverse effect of and underdosing of benzodiazepines Health Condition 2: T36- Poisoning by, adverse effect of and underdosing of systemic antibiotics
Conditions
Interventions
Intervention1: Ketamine: 0.5mg/kg infusion over 40 min only once
Control Intervention1: saline: infusion over 40 minutes only once
Sponsors
ESIC Medical College and Hospital, Hyderabad
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age: 18-60 years who attempted suicide and come to ESIC hospital emergency department. 2) Patients who has MADRS Score : 3) Patients who has SSI score : 4) Patients who has BIS-11 score > 65 5) Subjects who are co-operative and willing to give written informed consent for participation in the study.
Exclusion criteria
Exclusion criteria: 1) Patients with other active psychiatric disorders diagnosed according to ICD-10. 2)Patients who has MADRS Score : > 20 3) Patients who has SSI score : > 15 4) Patients who has BIS-11 score 5) History of any cardiovascular disease. 6) Any significant neurological disorder or insult. 7) Patients with acute physical illness. 8) Known or suspected pregnancy or lactation. 9) Patients with intra-cranial implants, pacemakers, cochlear implants, implantation of medication pumps.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Objectives : To assess the impact of Ketamine augmented Pharmacotherapy in decreasing Impulsivity.Timepoint: baseline, 24 hours, and 1 week,2 weeks, 12 weeks, 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Objectives : i) To study the prevalence of impulsive suicides among the suicidal attempts ii) To study Age, gender and education patterns in suicide attempts Timepoint: Baseline | — |
Countries
India
Contacts
Public ContactDr Vinil Marwel Gundu
ESI Medical College and Hospital, Sanath Nagar, Hyderabad.
Outcome results
None listed