Health Condition 1: K802- Calculus of gallbladder without cholecystitis
Conditions
Interventions
Intervention1: Remifentanil (Group R 1.0): 25 patients will be given Remifentanil infusion at a dose of 1 microgram/kg/minute during induction.
Intervention2: Remifentanil (Group R 0.5): 25 patients w
Sponsors
KPC Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients planned for any surgery requiring endotracheal intubation under general anaesthesia 2. Patients aged between 18 to 60 years 3. Patients with ASA grade I and II 4. Patients giving informed written consent
Exclusion criteria
Exclusion criteria: 1. Patients with a history of cardiac, pulmonary, renal, hepatic, cerebral or neuromuscular disease 2. Having an allergy to opioids or propofol 3. Chronic alcohol or drug abuse 4. A body mass index of 30 kg/m2 5. Pregnant patients 6. Age less than 18 years or more than 60 years
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the times taken to reach TOF 0 and TOFR 25% in groups R 0.5, R1 and S and to compare the results and therefore determine the optimal dose of Remifentanil infusion. Timepoint: TOF baseline, TOFR 25% and TOF 0 | — |
Secondary
| Measure | Time frame |
|---|---|
| To monitor hemodynamic response to laryngoscopy and intubation.Timepoint: Recorded at Baseline, at TOFR 25% and TOF 0 | — |
Countries
India
Contacts
Public ContactDr Subrata Ray
KPC Medical College & Hospital
Outcome results
None listed