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Compare effect of intravenous injection ondansetron and injection granisetron on spinal anaesthesia induce hypotension and bradycardia.

A comparative study of intravenous injection ondansetron and injection granisetron on spinal anaesthesia induce hypotension and bradycardia. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/02/080277
Enrollment
104
Registered
2025-02-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control Intervention1: Inj Granisetron 1 mg given intravenous prophylacticaly 5 minutes prior to spinal anaesthesia: Granisetron effectiveness in studying prevention of hypotension and bradycardia Con

Sponsors

BJMedical college AhmedabadGovernment of Gujurat
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologist (ASA) Classification grade I, II. 2. Patient willing to consent for surgery. 3. Weight of patient (40-60 kg).

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. History of allergy to local anaesthetic drugs and study drug. 3. Contraindications to spinal anaesthesia. 4. Patients with history of bleeding disorders or on anticoagulant therapy. 5. American Society of Anaesthesiologist (ASA) Classification III, IV and V. 6. Emergency surgeries.

Design outcomes

Primary

MeasureTime frame
This study is aimed to compare prevention of spinal anaesthesia induced hypotension and bradycardia in both drug groups.Timepoint: This study is aimed to compare incidence of hypotension and bradycardia in both drug groups intra operative and postoperative for upto 12 hours

Secondary

MeasureTime frame
Total dose of atropine & mephentermine required intra operatively.Timepoint: Any time of hypotension or bradycardia during intra op requirements of atropine & mephentermine.

Countries

India

Contacts

Public ContactDr Bhavana Raval

B.J. Medical College and Civil Hospital , Ahmedabad

drbhavanaraval@yahoo.com9426373182

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026