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Study related to One-Step Treatment to Close the Open Root Tip Using Different Materials

Clinical And Radiographic Evaluation Of Single Step Apexification Using Different Apical Barriers An In Vivo Study - nil

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080207
Enrollment
72
Registered
2025-02-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: 2 weeks after access opening and biomechanical preparation, Apexification will be done.: Intracanal medicament will be placed for 2 weeks for disinfection of the canal before placing MT

Sponsors

Ahmedabad dental corporation
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Permanent immature necrotic teeth due to trauma or due to dental caries resulting in open apex or blunderbuss canals requiring Root canal treatment. These cases might be associated with or without periapical lesion and associated with or without intraoral sinus tract.

Exclusion criteria

Exclusion criteria: Patients with significant medical comorbidity Presence of any evidence of root fracture

Design outcomes

Primary

MeasureTime frame
Cases of apexification done using apical barriers will show lesser or no extrusion of MTA allowing proper condensation against a firm barrier.Timepoint: Baseline, 1 week follow up

Secondary

MeasureTime frame
1. PRF being autologous should show faster healing by inducing growth factors which might lead to faster periapical healing in PRF group. 2. Collagen sponge by functioning as a scaffold and by enabling increased vascularization should show faster periapical healing.Timepoint: The outcome will be assessed after 3 months, 6 months and 12 months.

Countries

India

Contacts

Public ContactDr Sadhna Manglani

Government dental college and Hospital Ahmedabad

geetasthana@gmail.com9824440656

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026