Application and comparison of two medicinal gels in patients with gum disease after cleaning of teeth and assessing interleukin 1 beta marker before and after cleaning of teeth- a randomised controlled trial

A COMPARISON OF EFFICACY OF SUB-GINGIVAL DELIVERY OF NANOPARTICLE PROPOLIS GEL AND NANOCATECHIN GEL AS ADJUNCTS TO NON SURGICAL PERIODONTAL THERAPY ON INTERLEUKIN 1-BETA LEVELS IN CHRONIC PERIODONTITIS PATIENTS-A CLINICAL AND IMMUNOLOGICAL ASSAY - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080183

Enrollment

Registered

2025-02-10

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Group II (14): SRP along with application of nanoparticle propolis gel. : Baseline, 6 weeks and at 3 months Intervention2: Group III (14): SRP along with application of nanocatechin g

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 25 to 55 years. Probing Pocket Depth PPD greater than 5mm. Patients who have not received periodontal therapy, within preceding 6 months of the study

Exclusion criteria

Exclusion criteria: Patients who were on antibiotics/anti inflammatory drugs in the last 3 months. Pregnant and lactating females. Medically compromised patients. Smokers, tobacco chewers and alcoholics. Patients who are allergic to drugs.

Design outcomes

Primary

Measure	Time frame
Clinical improvement with both the gels. Which gel is superior to the other? Timepoint: Baseline 6 weeks 3 months	—

Secondary

Measure	Time frame
Clinical improvement with both the gels. Which gel is superior to the other? Timepoint: Baseline 6 weeks 3 months	—

Countries

India

Contacts

Public ContactRING GAHANA

Panineeya Mahavidyalaya institute of dental sciences and research centre

bindurakasi@gmail.com09959200225

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026